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Symbol
Name
ID

Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
MGI:1342774

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Type II diabetes mellitus
Disease(s) Associated with PPARGC1A	Type II diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes		abnormal crypts of Lieberkuhn morphology	endocrine/exocrine gland phenotype	increased adrenal gland weight	abnormal pancreatic beta cell morphology	increased pancreatic beta cell mass	enlarged pancreatic islets	increased thymus weight
Availability	Mouse Genotype	abnormal crypts of Lieberkuhn morphology	endocrine/exocrine gland phenotype	increased adrenal gland weight	abnormal pancreatic beta cell morphology	increased pancreatic beta cell mass	enlarged pancreatic islets	increased thymus weight
	Ppargc1a^tm1.1Amos/Ppargc1a^tm1.1Amos
	Ppargc1a^tm1Aztc/Ppargc1a⁺
	Ppargc1a^tm1Brsp/Ppargc1a^tm2Brsp Tg(Myog-cre)1Eno/0 (conditional)		*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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